Exploration of Wedelia trilobata, Acmella paniculata, Ageratum conyzoides, and Crassocephalum crepidiodes as Antibacterial Plants
Article Sidebar
-
antibacterial, Astersceae, zone of inhibition
Abstract
Some Asteraceae plants are reported to contain phytochemicals and to show high antibacterial activity. This study aims to determine the highest antibacterial activity of Wedelia trilobata, Acmella paniculata, Ageratum conyzoides, and Crassocephalum crepidiodes and to predict the chemical compounds that have a role as antibacterial. The samples were extracted with water and further fractionated using chloroform in the laboratory. Extracts determined the phytochemical compounds, antibacterial activity diffusion method, and compounds that have a role as antibacterial through literature review. Acmella paniculata demonstrated high antibacterial activities with the highest diameter of the zones of inhibition with a concentration of just 0.5 mg/disc. The compound that seems to have a role in antibacterial activity is spilanthol.
Full text article
References
[AOAC] The Association of Official Analytical Chemist. (2016). Official Methods of Analiysis (20th ed.). Association of Official Analytical Chemist.
Ayodele, O. O., Onajobi, F. D., & Osoniyi, O. R. (2020). Phytochemical Profiling of the Hexane fraction of Crassocephalum crepidioides Benth S. Moore leaves by GC-MS. African Journal of Pure and Applied Chemistry, 14(1), 1–8. https://doi.org/10.5897/ajpac2019.0815
Balekar, N., Nakpheng, T., & Srichana, T. (2014). Wedelia trilobata L.: A phytochemical and pharmacological review. Chiang Mai Journal of Science, 41(3), 590–605. http://epg.science.cmu.ac.th/ejournal/
Budiarti, E. (2019). Potensi Beberapa Ekstrak Asteraceae sebagai Antioksidan dan Antiglikasi [IPB University]. http://repository.ipb.ac.id/handle/123456789/99890
Calvin, B. Z., Abiodoun, O. P., Géorcelin, A. G., Laure, N. E., Bertrand, D. A., Blaise, A. A. G., & Sylvie, H.-A. (2016). In vitro anthelmintic activity of aqueous extract of Crassocephalum crepidioides (Benth.) S. Moore on Haemonchus contortus. Journal of Experimental and Integrative Medicine, 6(1). https://doi.org/10.5455/JEIM.061215.OR.144
Dubey, S., Maity, S., Singh, M., Saraf, S. A., & Saha, S. (2013). Phytochemistry, pharmacology and toxicology of spilanthes acmella: A review. In Advances in Pharmacological Sciences (Vol. 2013). Adv Pharmacol Sci. https://doi.org/10.1155/2013/423750
Ere, D., Pondei, K., Inaibo, Q., & Orutugu, L. (2014). Phytochemicals and Antimicrobial activity of plant parts of Ageratum conyzoides extracted using different solvents. Journal of Chemical, Biological and Physical Sciences, 4(4), 3429–3434. https://www.researchgate.net/publication/273393471%0APhytochemicals
Farhadi, F., Khameneh, B., Iranshahi, M., & Iranshahy, M. (2019). Antibacterial activity of flavonoids and their structure–activity relationship: An update review. In Phytotherapy Research (Vol. 33, Issue 1, pp. 13–40). Phytother Res. https://doi.org/10.1002/ptr.6208
Furtado, S. C., Costa, N. P., Corrêa, A. B., & Barcellos, J. F. M. (2018). Anti-Inflammatory Action of Spilanthes acmella : A Systematic Review. The Pharmaceutical and Chemical Journal, 5(3), 95–100. www.tpcj.org
Govindappa, M., Bharath, N., Shruthi, H. B., Sadananda, T. S., & Sharanappa, P. (2011). Antimicrobial, antioxidant and in vitro anti-inflammatory activity and phytochemical screening of Crotalaria pallida Aiton. African Journal of Pharmacy and Pharmacology, 5(21), 2359–2371. https://doi.org/10.5897/AJPP11.038
Gowri, J., Arockia, S. P., & Dharmalingam, V. (2014). Phytochemical Screening and Antimicrobial activity of different crude extracts of Wedelia biflora. Golden Research Thoughts, 4(6), 1–6.
Kamboj, A., & Saluja, A. K. (2008). Ageratum conyzoides L.: A review on its phytochemical and pharmacological profile. International Journal of Green Pharmacy (IJGP), 2(2). https://doi.org/10.22377/IJGP.V2I2.29
Lestari, T. (2015). Penetapan kadar polifenol dan aktivitas antibakteri ekstrak etanol daun Sintrong (Crassocephalum crepidiodes (Benth.) S.moore). Jurnal Kesehatan Bakti Tunas Husada, 13(1), 107–122. https://doi.org/10.36465/jkbth.v13i1.20
Mamidala, E., Gujjeti, R. P., Diseases, I., & Disorders, M. (2013). Phytochemical and Antimicrobial Activity of Acmella Paniculata Plant Extracts. Journal Biology Innovation, 2(1), 17–22.
Mardina, V., Halimatussakdiah, Harmawan, T., Ilyas, S., Tanjung, M., Aulya, W., & Nasution, A. (2020). Preliminary phytochemical screening of different solvent extracts of flower and whole plant of Wedelia biflora. IOP Conference Series: Materials Science and Engineering, 725(1). https://doi.org/10.1088/1757-899X/725/1/012077
Mokoka, T. A., McGaw, L. J., Mdee, L. K., Bagla, V. P., Iwalewa, E. O., & Eloff, J. N. (2013). Antimicrobial activity and cytotoxicity of triterpenes isolated from leaves of Maytenus undata (Celastraceae). BMC Complementary and Alternative Medicine, 13(1), 1–9. https://doi.org/10.1186/1472-6882-13-111
Morshed, M. A., Uddin, A., Saifur, R., Barua, A., & Haque, A. (2011). Evaluation of antimicrobial and cytotoxic properties of Leucas aspera and Spilanthes paniculata. International Journal of Biosciences, 1(2), 7–16. http://www.innspub.net
Okwori, A. E. J., Dina, C. O., Junaid, S., Okeke, I. O., Adetunji, J. A., & Olabode, A. O. (2006). Antibacterial Activities Of Ageratum conyzoides Extracts On Selected Bacterial Pathogens. The Internet Journal of Microbiology, 4(1), 1–8. https://doi.org/10.5580/A7072
Pasilala, F. B., Saleh, C., & Daniel. (2016). Uji Toksisitas (Brine Shrimp Lethality Test) dan Aktivitas Antioksidan dari Daun Sintrong (Crassocephalum crepidioides) dengan Metode 2,2-diphenyl-1-picrylhidrazil (DPPH). Jurnal Kimia Mulawarman, 14(1), 13–18. https://jurnal.kimia.fmipa.unmul.ac.id/index.php/JKM/article/view/253
Shailajan, S., Wadke, P., Joshi, H., & Tiwari, B. (2013). Evaluation of quality and efficacy of an ethnomedicinal plant Ageratum conyzoides L. in the management of pediculosis. Journal of Young Pharmacists, 5(4), 139–143. https://doi.org/10.1016/j.jyp.2013.10.005
Sutiknowati, L. I. (2016). Bioindikator pencemar, bakteri escherichia coli / lies Indah Sutiknowati. Oseana Majalah Ilmiah Semi Populer, 41(4), 63–71. https://lib.ui.ac.id
Syah, A. S., Sulaeman, S. M., & Pitopang, R. (2014). Jenis-Jenis Tumbuhan Suku Asteraceae Di Desa Mataue, Kawasan Taman Nasional Lore Lindu. Jurnal of Natural Science, 3(3), 297–312. https://doi.org/10.22487/25411969.2014.V3.I3.3340
Tabeo, D. F., Ibrahim, N., & Nugrahani, A. W. (2019). Etnobotani Suku Togian di Pulau Malenge Kecamatan Talatako, Kabupaten Tojo Una-Una, Sulawesi Tengah. Biocelebes, 13(1), 30–37. https://bestjournal.untad.ac.id/index.php/Biocelebes/article/view/12868
Voravuthikunchai, S. P., Phongpaichit, S., & Subhadhirasakul, S. (2005). Evaluation of antibacterial activities of medicinal plants widely used among AIDS patients in Thailand. Pharmaceutical Biology, 43(8), 701–706. https://doi.org/10.1080/13880200500385194
Wang, M., Firrman, J., Liu, L. S., & Yam, K. (2019). A review on flavonoid apigenin: Dietary intake, ADME, antimicrobial effects, and interactions with human gut microbiota. In BioMed Research International (Vol. 2019). Biomed Res Int. https://doi.org/10.1155/2019/7010467
Wegiera, M., Smolarz, H. D., Jedruch, M., Korczak, M., & Koproń, K. (2012). Cytotoxic effect of some medicinal plants from Asteraceae family on J-45.01 leukemic cell line - Pilot study. Acta Poloniae Pharmaceutica - Drug Research, 69(2), 263–268.
Yadav, R. (2012). Phytochemical Screening of Spilanthes acmella plant parts. International Journal of Pharmaceutical Erudition, 1(4), 44–72. www.pharmaerudition.org
Authors
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Copyright @2017. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted non-commercial used, distribution and reproduction in any medium