Formulation of Antioxidant Cream from Mung Bean (Vigna radiata L.) Seed Coat Extract
Abstract
The skin is the body’s primary barrier against free radicals, which can induce oxidative stress and premature ageing. Antioxidants neutralize these radicals. This study aims to formulate and evaluate a cream containing ethanol extract of mung bean (Vigna radiata L.) seed coat. Four formulations were prepared with extract concentrations of 10%, 15%, 20%, and 25%. Physical evaluations included organoleptic tests, homogeneity, pH, viscosity, cream type, spreadability, and adhesiveness. Antioxidant activity was measured using the DPPH method. All formulations met physical standards, and formula F4 (25%) showed the highest antioxidant activity with an IC₅₀ value of 79.49 ppm. These findings indicate the potential of mung bean seed coat extract as an active antioxidant agent in topical preparations.
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References
Ahmad, Z., & Damayanti. (2018). Penuaan kulit: Patofisiologi dan manifestasi klinis. Berkala Ilmu Kesehatan Kulit dan Kelamin, 30(3), 208–215. https://doi.org/10.20473/bikk.V30.3.2018.208-215
Awalludin, A., Tungadi, R., & Djuwarno, E. N. (2022). Formulasi dan evaluasi stabilitas fisik krim minyak biji kelor (Moringa oleifera L.). Journal of Experimental and Clinical Pharmacy (JECP), 2(2), 144–150. http://dx.doi.org/10.52365/jecp.v2i2.433
Cao, D., Li, H., Yi, J., Zhang, J., Che, H., Cao, J., & Yang, L. (2011). Antioxidant properties of the mung bean flavonoids on alleviating heat stress. PLoS ONE, 6(6), e21071. https://doi.org/10.1371/journal.pone.0021071
Ermawati, D. E. (2017). Optimization of emulsifier composition of water-in-oil emulsion of strawberry fruits (Fragaria vesca L.) based on simplex lattice design method. JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2(2), 78–84. https://doi.org/10.20961/JPSCR.V2I2.14398
Fodor, L., & Ullmann, Y. (2019). Aesthetic applications of intense pulsed light. In Aesthetic Applications of Intense Pulsed Light. Springer.
Hayati, R., & Vanira, J. (2021). Formulasi krim ekstrak etanol umbi bawang dayak (Eleutherine palmifolia (L.) Merr) dan efektivitasnya terhadap Staphylococcus aureus. Jurnal Ilmiah Farmasi Simplisia, 1(1), 1–7.
Maesaroh, K., Kurnia, D., & Al Anshori, J. (2018). Perbandingan metode uji aktivitas antioksidan DPPH, FRAP dan FIC terhadap asam askorbat, asam galat dan kuersetin. Chimica et Natura Acta, 6(2), 93–98. https://doi.org/10.24198/cna.v6.n2.19049
Muthia, R., Saputri, R., & Verawati, S. A. (2019). Uji aktivitas antioksidan ekstrak etanol kulit buah mundar (Garcinia forbesii King.) menggunakan metode DPPH. Jurnal Pharmascience, 6(1), 74–80. https://doi.org/10.31942/jiffk.v16i01.2923
Pratasik, M. C. M., Yamlean, P. V. Y., & Wiyono, W. I. (2019). Formulasi dan uji stabilitas fisik sediaan krim ekstrak etanol daun sesewanua (Clerodendron squamatum Vahl.). Pharmacon, 8(2), 261–269. https://doi.org/10.35799/pha.8.2019.29289
Pratiwi, P. Y., Mardiyaningsih, A., Ismiyati, N., & Setiyawan, H. (2021). Aktivitas antibakteri ekstrak etanolik, fraksi n-heksan, dan fraksi kloroform daun binahong (Anredera cordifolia) terhadap bakteri Escherichia coli serta penapisan fitokimianya. Jurnal Jamu Indonesia, 6(2), 84–91. https://doi.org/10.29244/jji.v6i2.207
Rahayu, P., Monica, E., & Yulinda Cesa, F. (2023). Formulasi dan evaluasi sediaan krim pelembap dan antioksidan kombinasi ekstrak kulit buah manggis (Garcinia mangostana L.) dan lidah buaya (Aloe vera L.). Sainsbertek, 3(2), 52–65. https://doi.org/10.33479/sb.v3i2.234
Rikadyanti, R., Sugihartini, N., & Yuliani, S. (2020). Sifat fisik krim tipe M/A ekstrak etanol daun kelor (Moringa oleiferaL.) dengan variasi konsentrasi menggunakan emulgator asam stearat dan trietanolamin. Media Farmasi Poltekkes Makassar, 16(1), 88–95. https://doi.org/10.32382/mf.v16i1.1423
Saryanti, D., Setiawan, I., & Safitri, R. A. (2019). Optimasi formula sediaan krim M/A dari ekstrak kulit pisang kepok (Musa acuminata L.). Jurnal Riset Kefarmasian Indonesia, 1(3), 225–237.
Suparmi, S., Anshory, H., & Dirmawati, N. (2012). Uji aktivitas antioksidan ekstrak etanol kulit buah rambutan (Nephelium lappaceum L.) dengan metode linoleat-tiosianat. Jurnal Ilmiah Farmasi, 9(1), 1–10.
Suryani, S., Amalia, R., Fajriati, J. R., Febrianto, Y. E., Aziizah, R. N., Kahla, M. G., Hanifa, R. I. Z., & Anjali, I. S. (2023). Aktivitas antioksidan dan inhibitor nitrit oksida ekstrak etanol kulit biji kacang hijau (Vigna radiata L.). Kartika: Jurnal Ilmiah Farmasi, 8(2), 109–119. https://doi.org/10.26874/kjif.v8i2.712
Tajoddin, M., Shinde, M., & Lalitha, J. (2010). Polyphenols of mung bean (Phaseolus aureus L.) cultivars differing in seed coat color: Effect of dehulling. Journal of New Seeds, 11(4), 369–379. http://dx.doi.org/10.1080/1522886X.2010.520146
Yahya, N. A., Abdul Wahab, R., Attan, N., Abdul Hamid, M., Mohamed Noor, N., & Kobun, R. (2022). Ananas comosuspeels extract as a new natural cosmetic ingredient: Oil-in-water (O/W) topical nano cream stability and safety evaluation. Evidence-Based Complementary and Alternative Medicine, 2022, 1–10. https://doi.org/10.1155/2022/2915644
Zheng, Y., Liu, S., Xie, J., Chen, Y., Dong, R., Zhang, X., Liu, S., Xie, J., Hu, X., & Yu, Q. (2020). Antioxidant, α-amylase and α-glucosidase inhibitory activities of bound polyphenols extracted from mung bean skin dietary fiber. LWT, 132, 109943. https://doi.org/10.1016/j.lwt.2020.109943
Zhou, Y., Zheng, J., Gan, R. Y., Zhou, T., Xu, D. P., & Li, H. B. (2017). Optimization of ultrasound-assisted extraction of antioxidants from the mung bean coat. Molecules, 22(4), 1–13. https://doi.org/10.3390/molecules22040638
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