Jurnal Jamu Indonesia https://jamu-journal.ipb.ac.id/index.php/JJI <p> </p> <div id="main-content" class="page_index_journal" role="content"> <div class="journal-description"> <div class="table-wrapper"> <table class="table" width="756"> <tbody> <tr> <td width="193"><strong>Journal Title</strong></td> <td width="9">:</td> <td width="544">Jurnal Jamu Indonesia (JJI) or Indonesian Journal of Jamu</td> </tr> <tr> <td width="193"><strong>Abbreviation</strong></td> <td width="9">:</td> <td width="544">JJI</td> </tr> <tr> <td width="193"><strong>Scope</strong></td> <td width="9">:</td> <td width="544">Herbal Medicine</td> </tr> <tr> <td width="193"><strong>Type of manuscript</strong></td> <td width="9">:</td> <td width="544">Regular paper, Research notes, Short communication, Technical paper, Book review, Opinion</td> </tr> <tr> <td width="193"><strong>Frequency</strong></td> <td width="9">:</td> <td width="544"><span style="font-weight: 400;">JJI is published three times a year</span></td> </tr> <tr> <td width="193"><strong>DOI</strong></td> <td width="9">:</td> <td width="544"><a href="https://doi.org/10.29244/jji.v8i2">10.29244/jji.v8i2.332</a></td> </tr> <tr> <td width="193"><strong>Print ISSN</strong></td> <td width="9">:</td> <td width="544"><a href="https://portal.issn.org/resource/issn/2407-7178">2407-7178</a></td> </tr> <tr> <td width="193"><strong>Online ISSN</strong></td> <td width="9">:</td> <td width="544"><a href="https://portal.issn.org/resource/issn/2407-7763">2407-7763</a></td> </tr> <tr> <td width="193"><strong>Publisher</strong></td> <td width="9">:</td> <td width="544">TropBRC IPB University</td> </tr> <tr> <td width="193"><strong>Language</strong></td> <td width="9">:</td> <td width="544">English</td> </tr> <tr> <td width="193"><strong>Citation Analysis</strong></td> <td width="9">:</td> <td width="544"><a href="https://sinta.kemdikbud.go.id/journals/profile/3747">Sinta</a>, <a href="https://scholar.google.com/citations?hl=en&amp;user=R4VadkgAAAAJ&amp;view_op=list_works&amp;sortby=pubdate">Google Scholar</a></td> </tr> <tr> <td width="193"><strong>Open Access Policy</strong></td> <td width="9">:</td> <td width="544"><a href="https://journal.ipb.ac.id/index.php/konservasi/OpenAccessandCopyright">Creative Commons Attribution (CC BY)</a></td> </tr> <tr> <td width="193"><strong>Preservation Archiving</strong></td> <td width="9">:</td> <td width="544"><a href="#">PKP PN</a></td> </tr> </tbody> </table> </div> <p><strong>Jurnal Jamu Indonesia (JJI) or Indonesian Journal of Jamu</strong> is dedicated to the exchange of information and widespread scientific understanding regarding the development of the world of herbal medicine through the publication of scientific papers. The themes of scientific papers within the scope of JJI include the theme of herbal medicine research from upstream to downstream which is not limited to ethnobotanical research and local knowledge, exploration, conservation, domestication of biological resources related to herbal medicine, variety breeding, development of Good Agricultural and Collection Practices (GACP) for herbal medicine raw materials, development of standards for raw materials and herbal medicine products, development of herbal medicine products, identification of active compounds and their synthesis, working mechanisms for the bioactivity of herbal medicine formulas, social and economic aspects related to the development of herbal medicine.</p> </div> </div> Tropical Biopharmaca Research Center, IPB University en-US Jurnal Jamu Indonesia 2407-7178 <p><a href="http://creativecommons.org/licenses/by-nc-sa/4.0/" rel="license"><img style="border-width: 0;" src="https://i.creativecommons.org/l/by-nc-sa/4.0/88x31.png" alt="Creative Commons License"></a><br>This work is licensed under a <a href="http://creativecommons.org/licenses/by-nc-sa/4.0/" rel="license">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License</a>. <span style="font-weight: 400;">Copyright @2017. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (</span><a href="http://creativecommons.org/licenses/by-nc-sa/4.0/"><span style="font-weight: 400;">http://creativecommons.org/licenses/by-nc-sa/4.0/</span></a><span style="font-weight: 400;">) which permits unrestricted non-commercial used, distribution and reproduction in any medium </span></p> Modernization of Herbal Medicine (Jamu): Integrating Indonesian Herbal Compounds in Drug Design Through Structural-Based Techniques https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/333 Setyawati Inda Copyright (c) 2024 Jurnal Jamu Indonesia 2024-05-03 2024-05-03 9 2 52 54 10.29244/jji.v9i2.333 Table of Contents https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/335 Jurnal Jamu Indonesia JJI Copyright (c) 2024 2024-05-03 2024-05-03 9 2 Phytochemical Analysis and Determination of MIC and MFC of Cacao Leaves Extract (Theobroma cacao L.) against Malassezia furfur https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/316 <p>Pityriasis versicolor is a disease caused by <em>Malassezia furfur</em>. One of the plants that can potentially act as antifungal is cacao leaves (<em>Theobroma cacao </em>L.), which contain several secondary metabolite compounds, including alkaloids, flavonoids, tannins, quinones, terpenoids, and saponins. This study aims to determine the phytochemical analysis and the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of cacao leaves ethanolic extract against <em>M. furfur</em>. Extracts were obtained by maceration using 70% ethanol and phytochemicals analysis using Herborne’s method. Furthermore, the extracts were made into concentrations’ variations of 3.125%; 6.25%; 12.5%; 25%; 50%; and 100% for testing antifungal activity, with 10% DMSO as negative control and 2% Ketoconazole and Itraconazole as positive controls. MIC was performed with liquid macrodilution method, and MFC was performed with spread method. The results of phytochemical analysis showed that the extract contained alkaloids, flavonoids, phenols, tannins, quinones, terpenoids and saponins. MIC value was obtained at concentration of 50% and MFC value was obtained at 100%. Cacao leaves ethanolic extract with concentration of 50% can inhibit <em>M. furfur</em><em>’s</em> growth and with 100% can eliminate <em>M. furfur</em>.</p> Siti Marwah Lestari Leonyta Camelia Widya Twini Rizki Septa Pratama Chindiana Khutami Amraini Amelia Rahmadevi Rahmadevi Yuni Andriani Copyright (c) 2024 Jurnal Jamu Indonesia 2024-05-03 2024-05-03 9 2 53 66 10.29244/jji.v9i2.316 Antibacterial Activity of Ethanol, Ethyl Acetate, and n-Hexane Extracts of Bidara Laut Lignum (Strychnos lucida R.Br) against Staphylococcus aureus and Escherichia coli https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/283 <p><em>Strychnos lucida</em> is empirically believed to have efficacy in treating various diseases such as fever, malaria, toothache, and stomachache and to treat wounds. The secondary metabolite of <em>Strychnos lucida</em> has various polarity. The purpose of this study was to compare the inhibitory activity of <em>Strychnos lucida</em> extracts against <em>E. coli</em> and <em>S. aureus</em> bacteria. The test was carried out by measuring the Diameter of the Inhibitory Region (DIR) using the disc diffusion method on a concentration of 90%, 75%, 60%, 45%, 30%, and 15%. The Minimum Inhibitory Concentration (MIC) was carried out by agar dilution method on a concentration of 15%, 12.5%, 10%, 7.5%, 5%, and 2.5%. The positive control was 1% ampicillin, and the negative control was 10% DMSO. The ethyl acetate extract showed the highest DIR of 14.30 mm against <em>S. aureus</em> and <em>E. coli</em> on a concentration of 45%, ethanol extract was 8,38 mm against <em>S. aureus</em> and 8.71 mm against <em>E. coli</em>, and n-hexane had no inhibitory activity on a concentration 45%. The result of the MIC test for ethanol and ethyl acetate extract for both bacteria was found at a concentration of 15%, while n-hexane extract against <em>Staphylococcus aureus</em> was found at a concentration of 90% and a concentration of 75% against <em>Escherichia coli</em>.</p> Erwi Putri Setyaningsih Saiful Bahri Rindang Nurjanah Copyright (c) 2024 Jurnal Jamu Indonesia 2024-05-03 2024-05-03 9 2 67 72 10.29244/jji.v9i2.283 The Business Development Strategy of Jamu at PT. Firdaus Kurnia Indah (FKI) in Bangkalan Regency https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/306 <p class="22Abstract"><span lang="EN-US">Jamu is a traditional medicine that Indonesians have consumed for generations. Several herbal medicine industries in the Bangkalan district have difficulty surviving and developing their businesses. This study aims to determine the strategy for developing the herbal medicine business at PT. FKI, Bangkalan. This research is part of the MBKM-KWU UTM Agricultural Agribusiness Study Program in 2022, which is carried out in the form of a one-month internship as preliminary research. Data was collected from March to June 2023 using questionnaires and deep interviews with respondents. The 4C diamond, SWOT, and QSPM analysis are used to determine strategies that can be implemented for PT. FKI. Internally, the main strength is using natural ingredients, and a shortage of product stock is the main weakness. Assessment of external factors reveals that technological progress, especially social media, is the main opportunity, while the main threat faced is the existence of similar competitors. PT. FKI is in an aggressive strategic position to increase competitiveness by exploiting the company's opportunities and strengths.</span></p> Yunita Eka Dyah Pratiwi Setiani Setiani Ifan Rizky Kurniyanto Copyright (c) 2024 Jurnal Jamu Indonesia 2024-05-03 2024-05-03 9 2 73–84 73–84 10.29244/jji.v9i2.306 Consumer Profiles and Drink Menus Made from Medicinal Plants at the Jamu Cafe in Depok Sleman District, Yogyakarta https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/310 <p class="22Abstract"><span lang="EN-US">The use of medicinal plants as ingredients in making drinks in cafes is increasing along with the number of cafes. Herbal café makes a unique menu using medicinal plants in drink recipes to produce a distinctive taste, color, and aroma. This research aims to identify visitor profiles and drink menus made from medicinal plants and explore the understanding of visitors and cafe owners regarding the benefits of medicinal plants added to drinks. The research data collection technique uses a questionnaire equipped with an interview sheet. The questionnaires and interview sheets used have been tested for language comprehension and validity. The research was conducted at 272 cafes in Depok District, Sleman Regency, Special Region of Yogyakarta. The sample was determined using purposive sampling, data was collected after obtaining ethical clearance approval from the Health Research Ethics Committee Team. Data was obtained through filling out surveys by visitors and cafe owners, complemented by interviews with cafe owners. Data was collected three times: August, September, and October 2023. Data analysis was carried out descriptively and qualitatively. Most herbal cafe visitors (70%) are aged between 21–30 years with the majority of professions (44%) being students. The source of information about herbal cafe menus was mostly obtained (56%) from friends or family, and the frequency of visits to cafes was mostly (82%) between 1–5 times per month. More than 98% of visitors stated the benefits of medicinal plants in the drink menu, namely as a refresher or body warmer. There are 14 types of medicinal plants used as ingredients in the herbal cafe's drink menu, with a total monthly requirement for all medicinal plants of 545.1 kilograms; ginger ranks among the highest requirements. Recipe information for the menu was obtained from the family, the Ministry of Health Republic Indonesia website, and the herbal cafe owner made the recipe independently.</span></p> Yustina Sri Hartini Agustina Setiawati Yohanes Dwiatmaka Copyright (c) 2024 Jurnal Jamu Indonesia 2024-05-03 2024-05-03 9 2 85–94 85–94 10.29244/jji.v9i2.310 In Silico Study of Bioactive Compounds in Herba Sambiloto (Andrographis paniculata Burm. F. Nees) as HIV-1 Reverse Transcriptase Inhibitor https://jamu-journal.ipb.ac.id/index.php/JJI/article/view/300 <p>A medicinal plant known as sambiloto (<em>Andrographis paniculata</em> Burm. F. Nees) contains certain active compounds that potentially are anti-HIV. However, it is not yet known which compounds are involved in inhibiting HIV activity. This study aimed to identify potentially active compounds from the sambiloto plant that could inhibit the HIV-1 reverse transcriptase enzyme using the in-silico method. In silico methods that will be carried out are internal validation, molecular docking, ADMET prediction, and molecular dynamics. The molecular docking results showed that the five best compounds have potential as anti-HIV drugs compared to <em>efavirenz</em> with the rerank score -152.119 until -125.177 kcal/mol. In contrast, the rerank score of the comparison ligand is -94.7639 kcal/mol. The ADMET prediction showed that the selected compounds have a good pharmacokinetics profile and are nontoxic. The molecular dynamic results showed that deoxy-11,12-didehydro<em>andrographiside</em> and andropraphiside are stable and have potential as anti-HIV drugs with average RMSD values of 1.88 and 2.02 Å while the comparison ligand is 1.67 Å.</p> Andri Prasetiyo Titiek Martati Putri Windari Saputra Copyright (c) 2024 Jurnal Jamu Indonesia 2024-05-03 2024-05-03 9 2 95–105 95–105 10.29244/jji.v9i2.300